Application value of serum procalcitonin, white blood cell count, C-reactive protein combined with bacterial blood culture detection on infected patients
WANG Xiaofang FENG Wansheng ZHOU Hongcui QIU Yongjia
Department of Clinical Laboratory, People′s Hospital of Wuzhou, Guangxi Zhuang Autonomous Region, Wuzhou 543000, China
Abstract：Objective To analyze the value of serum procalcitonin (PCT), white blood cell count (WBC), C-reactive protein (CRP) combined with bacterial blood culture in the detection on infectious patients. Methods From December 2015 to December 2017, 153 infected patients in People's Hospital of Wuzhou were selected. According to blood culture results, patients were divided into blood culture positive group and blood culture negative group, the blood culture positive group were Gram-positive coccus group, Gram-negative bacillus group and other miscellaneous bacteria group, 100 normal healthy people were selected as control group at the same periord. All objects were given PCT, WBC, and CRP examination, then the results were compared and analyzed. Results Among 153 infected patients, 72 cases were blood culture positive (blood culture positive group), 81 cases were blood culture negative (blood culture negative group). The levels of PCT, WBC, CRP in blood culture positive group were higher than the blood culture negative group, and the levels of PCT, WBC, CRP in the blood culture positive group and blood culture negative group were higher than normal control group, the differences were statistically significant (P < 0.05). There were 48 cases were Gram-negative bacilli in the blood culture positive group, 13 cases were Gram-positive cocci, and 11 cases were other strains. The levels of PCT and WBC in Gram-positive cocci group were compared with Gram-negative bacilli group, other strains group, the differences were not statistically significant (P ＞ 0.05), CRP levels were comapred, the differences were statistically significant (P < 0.05), the levels of PCT, WBC, CRP in Gram-negative bacilli group were compared with other strains group, the differences were not statistically significant (P ＞ 0.05). Conclusion PCT, WBC and CRP are indicators of bacterial infection, but it is not a good way to distinguish which type of bacteria. The combined blood culture test has important clinical application value for diagnosis and treatment of bacterial infection.
2018, Vol. 15 
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