Effect of cold storage time on the stability of biochemical project
LI Ronghai1# YAO Xingwei2# QIU Congying3 YANG Qi2 LU Xin2 ZHANG Ze2 GUO Heng2 WANG Bin2▲
1.Department of Clinical Laboratory, Xiyuan Hospital, CACMS, Beijing 100091, China;
2.Department of Clinical Laboratory, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China;
3.Department of Clinical Laboratory, Beijing Bo′ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
Abstract：Objective To evaluate the stability and repeatability of every 24 hours biochemical project in the serum samples for 7 days, in order to provide good advice and guidance for clinicians. Methods From January to December in 2017, 30 cases of clinical serum samples from Xiyuan Hospital were collected, and Roche Cobas 8000 automatic analyzer was used for the detection. The samples were stored at 4℃ after being detected with 44 biochemical projects every day in the study, such as glucose (GLU), creatinine (Cr) and C-reactive protein (CRP). Results The detection results of K+, Cl-, Na+, C3, CK-MB, LDH in 24 h were significantly different from those of other time periods, and the differences were statistically significant (P < 0.05). The concentration of K+, Cl-, Na- and complement C3 were significantly increased, while the levels of CK-MB and LDH were significantly decreased. However, the level of other 38 testing projects had not statistically significant (P > 0.05). Conclusion It is important for medical workers to know the changes of some biochemical markers in serum samples during one week, especially the changing concentration of K+, Cl-, Na-, complement C3, CK-MB and LDH.
李荣海1# 姚兴伟2# 邱聪颖3 杨琦2 卢欣2 张泽2 郭姮2 王斌2▲. 血清标本冷藏时间对生化项目稳定性的影响[J]. 中国医药导报, 2018, 15(19): 143-146.
LI Ronghai1# YAO Xingwei2# QIU Congying3 YANG Qi2 LU Xin2 ZHANG Ze2 GUO Heng2 WANG Bin2▲. Effect of cold storage time on the stability of biochemical project. 中国医药导报, 2018, 15(19): 143-146.
2018, Vol. 15 
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