Diagnosis and treatment of a cases with influenza-associated acute necrotizing encephalopathy and review of relevant literature and review of relevant literature
SUN Wenqiang1 ZHU Xueping1 FU Changchang1 LI Ying2 SHENG Mao3
1.Department of Neonatology, Children’s Hospital of Soochow University, Jiangsu Province, Suzhou 215025, China;
2.Department of Intensive Care Unit, Children’s Hospital of Soochow University, Jiangsu Province, Suzhou 215025, China;
3.Department of Imaging, Children’s Hospital of Soochow University, Jiangsu Province, Suzhou 215025, China
Abstract：influenza-associated acute necrotizing encephalopathy (IANE) is one of the most critical subtypes of an acute encephalopathy, progressing rapidly, with fever, convulsions, and rapid onset of consciousness the most common, and with a poor prognosis. In order to improve clinicians’ ability to recognize and diagnose IANE at an early stage, ensure timely treatment of patients and improve their prognosis. In this paper, analyze and discuss a patient with IANE who was seen in the Children’s Hospital of Soochow University. The child started with a high fever and showed symptoms of neurological involvement within two days. The brain MRI showed bilateral symmetrical brain damage, and the diagnosis of IANE was considered in combination with relevant laboratory tests. The child was discharged after aggressive treatment but was left with mild cognitive impairment. Through a retrospective analysis of the national and international literature, it is mainly believed that early use of intravenous glucocorticoid shock combined with Oseltamivir antiviral, as well as the use of appropriate antibiotics against infection, is the best treatment regimen for IANE.
孙文强1 朱雪萍1 傅嫦嫦1 李莺2 盛茂3. 儿童乙型流感相关急性坏死性脑病1例的诊治及文献回顾分析[J]. 中国医药导报, 2023, 20(21): 183-186.
SUN Wenqiang1 ZHU Xueping1 FU Changchang1 LI Ying2 SHENG Mao3. Diagnosis and treatment of a cases with influenza-associated acute necrotizing encephalopathy and review of relevant literature and review of relevant literature. 中国医药导报, 2023, 20(21): 183-186.
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