Endoscopic manifestations and endoscopic treatments of esophageal granular cell tumors
ZHENG Xiaoling1 PAN Dangling2 LIANG Wei1 ZHONG Shishun1 GAO Liying1
1.Gastrointestinal Endoscopy Center, Fujian Provincial Hospital of Fujian Medical University, Fujian Province, Fuzhou, 350001,China;
2.Department of Pathology, Fujian Provincial Hospital of Fujian Medical University, Fujian Province, Fuzhou 350001,China
Abstract：Objective To investigate endoscopic features and the efficacy and safety of endoscopic treatments of esophageal granular cell tumors (GCTs). Methods Patients with GCTs who were underwent endoscopic resection and confirmed by pathology in Gastrointestinal Endoscopy Center of Fujian Provincial Hospital from January 2004 to June 2016 were selected as the study object, testing results of endoscopy, endoscopic ultrasonography examination characteristics and endoscopic treatment were observed and follow-up results were analyzed. Results There were 19 patients with esophageal GCTs in this study,included 8 males and 11 females. The patients were between 39 and 65 years old, with an average age of (50.12±9.37) years old. The lesions exhibited yellowish or white lump with smooth surface in gastroscopy, all cases presented low echo changes in endoscopic ultrasonography.14 cases were derived from mucosa and muscularis mucosa, 5 cases were derived from submucosa, the diameters of these lesions were 0.6-3.0 cm with an average of (0.8±0.57) cm. 16 cases of patients with endoscopic mucosal resection (EMR) and Three patients of endoscopic submucosal dissection (ESD), no patient showed the complications associated with endoscopic therapy. The patients were followed up for 7-144 months, with the median of 74 months, no tumor recurrence or metastasis was observed during the follow-up period. Conclusion Endoscopy and endoscopic ultrasonography are important methods for the diagnosis of esophageal GCTs, EMR and ESD are safe and effective for the treatment of esophageal GCTs.
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2017, Vol. 14 
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