Evaluation of depression and anxiety in patients with conjunctivochalasis
LIU Jiang1 SHA Yongyi2 ZHANG Wei2 KONG Xueqing2 XIANG Minhong2
1.Department of Ophthalmology, Pudong New Area Eye Disease and Dental Disease Prevention, Shanghai 201301, China; 2.Department of Ophthalmology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China
Abstract：Objective To investigate the changes of emotional states such as depression and anxiety in patients with conjunctivochalasis. Methods A total of 260 patients diagnosed with conjunctivochalasis were collected from the Department of Ophthalmology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from September 2020 to February 2022. The depression and anxiety status were assessed by patient health questionnaire (PHQ-9) and general anxiety disorder scale (GAD-7), respectively, and the degree of ocular surface discomfort was assessed by ocular surface disease index (OSDI). Schirmer Ⅰ test (SIT), tear film rupture time (BUT), and corneal fluorescein staining (FL) were used to evaluate ocular surface signs. Results There were significant differences in age and proportion of diabetes among different clinical grades (P＜0.05). The PHQ-9 and GAD-7 scores of patients with different clinical grades were compared, and the differences were statistically significant (P＜0.05). Correlation analysis showed that OSDI score was posi- tively correlated with PHQ-9 and GAD-7 scores (r＞0, P＜0.05). SIT was negatively correlated with PHQ-9 and GAD-7 scores (r＜0, P＜0.05). BUT was negatively correlated with PHQ-9 and GAD-7 scores (r＜0, P＜0.05). FL scores were positively correlated with PHQ-9 and GAD-7 scores (r＞0, P＜0.05). Logistic regression analysis showed that PHQ-9 and GAD-7 scores were independent risk factors for conjunctival relaxation (OR=1.350, 1.852, P＜0.05). There was statistical significance in the proportion of depression and anxiety among different genders (P＜0.05). Conclusion The higher the clinical grade, the more serious the degree of depression and anxiety, and the more severe the symptoms of ocular surface discomfort. Women are more likely to have depression and anxiety than men. In the treatment of conjunctivochalasis, we should pay attention to the evaluation of the patient’s psych- ological state, so as to achieve the comprehensive treatment of the disease.
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2023, Vol. 20 
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