Abstract：Objective To explore the epidemiological characteristics of hypothyroidism in pregnancy, and to analyze its influencing factors. Methods The clinical data of 1000 pregnant women who were admitted to Dingzhou People′s Hospital in Hebei Province from December 2017 to December 2018 were retrospectively selected. The prevalence of hypothyroidism in pregnancy was screened. Univariate and multivariate logistic regression were used to analyze the influencing factors of hypothyroidism in pregnancy. Results Of the 1000 pregnant women included in this study, 392 pregnant women had hypothyroidism, the prevalence rate was 39.20%. Among them, 127 pregnant women had clinical hypothyroidism, accounting for 32.40%, 265 pregnant women had subclinical hypothyroidism, accounting for 67.60%. Univariate analysis showed that the incidence of hypothyroidism in pregnancy with age≥30 years, number of pregnancies≥2 times, education below junior college, parity≥3 times, history of spontaneous abortion, diabetes mellitus, hypertensive disorder of pregnancy, low iodine intake, thyroid peroxidase antibody positive, birth interval≥48 months were higher (P < 0.05). Multivariate logistic regression analysis showed that age≥30 years, number of pregnancies≥2 times, education below junior college, parity≥3 times, history of spontaneous abortion, diabetes mellitus, hypertensive disorder of pregnancy, low iodine intake, birth interval≥48 months were independent risk factors for hypothyroidism in pregnancy (P < 0.05). Conclusion Hypothyroidism has a high prevalence rate in pregnant women, which should be detected early and given high attention clinically. They can make scientific preventive measures to reduce the occurrence of disease according to its influencing factors
蔡乐男1,2 王盼3 徐月清1. 妊娠期甲状腺功能减退症的流行病学调查研究[J]. 中国医药导报, 2020, 17(15): 108-111.
CAI Le′nan1,2 WANG Pan3 XU Yueqing1. Investigation study on the epidemiological of hypothyroidism in pregnancy. 中国医药导报, 2020, 17(15): 108-111.
2020, Vol. 17 
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