Analysis of clinical effects of initial periodontal treatment and Triamcinolone Acetonide oral ointment on gingival lichen planus
WANG Xiang1 ZHANG Peng2 ZHENG Lichun3 WANG Wenmei1 DUAN Ning1 CHU Zhijuan1
1.Department of Oral Mucosal Diseases, Nanjing Stomatological Hospital Medical School of Nanjing University, Jiangsu Province, Nanjing 210008, China; 2.Department of Periodontal Disease Division, Nanjing Stomatological Hospital Medical School of Nanjing University, Jiangsu Province, Nanjing 210008, China; 3.Department of Preventive Stomatology, Nanjing Stomatological Hospital Medical School of Nanjing University, Jiangsu Province, Nanjing 210008, China
Abstract：Objective To analyze the clinical effect of periodontal therapy combined with Triamcinolone Acetonide for treatment of lichen planus gingiva. Methods From January to September in 2019, 40 patients affected with gingival lichen planus and chronic periodontitis diagnosed in the clinics of Nanjing Stomatological Hospital Medical School of Nanjing University, according to the random number table method, the patients were randomly divided into the treatment group and the control group, with 20 patients in each group. The treatment group was treated with periodontal therapy combined with topical triamcinolone acetonide oral ointment, while the control group was treated with topical triamcinolone acetonide oral ointment. Both groups were given the drug for three months, the pain degree, lesion area and total effective rate before and after treatment were observed. Results The pain degree of patients in different time and groups was different, and there was interaction between time and groups, and the differences were statistically significant (P ＜ 0.05). Further pair comparison and intra-group comparison: the pain degree of the two groups at one week, two weeks, one month and six months after treatment were lower than those before treatment, and the difference were statistically significant (P ＜ 0.05). Comparison between groups: one week and two weeks after treatment, the pain degree of the treatment group was lower than that of the control group, with statistically significant differences (P ＜ 0.05). The lesion area was different at different times, and the difference was statistically significants (P ＜ 0.05); there was interaction between time and groups, and the difference was statistically significant (P ＜ 0.05). Further pairwise comparison and intra-group comparison: the lesion area at one week, two weeks, one month and six months after treatment were smaller than that before treatment, and the differences were statistically significant (P ＜ 0.05). Two weeks, one month and six months after treatment, the lesion area of the treatment group were smaller than that of the control group, with statistically significant differences (P ＜ 0.05). The total effective rate of the treatment group at one, two weeks, one month and six months after treatment were higher than those of the control group, and the differences were statistically significant (P ＜ 0.05). Conclusion Periodontal basic treatment combined with Triamcinolone Oral Ointment for lichen planus gingival has quick short-term effect, good maintenance effect and good long-term effect.
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2020, Vol. 17 
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