Effect of Xingbei Zhike Granules in the adjuvant treatment of children with acute bronchitis
DONG Wenfang1* WANG Wenyu2* LIN Jie1 WU Yufen1 YUAN Shuhua1 ZHANG Hao1 ZHANG Bin2
1.Department of Respiratory, Shanghai Children’s Medical Center Affiliated to Medical College of Shanghai Jiaotong University, Shanghai 200127, China; 2.Department of Gastroenterology, Shanghai Children’s Medical Center Affiliated to Medical College of Shanghai Jiaotong University, Shanghai 200127, China
Abstract：Objective To observe the effect of Xingbei Zhike Granules combined with Western medicine in the adjuvant treatment of children with acute bronchitis. Methods One hundred and eight children with acute bronchitis diagnosed by Shanghai Children’s Medical Center Affiliated to Shanghai Jiaotong University Medical College from January to December 2019 were divided into control group and treatment group according to random number table method, 54 cases in each group. Control group was given conventional Western medicine treatment, namely anti infection and symptomatic treatment; treatment group was given Xingbei Zhike Granules at the same time. The course of treatment was one week. The clinical outcome was followed up. Cough symptom score, fever regression time, pulmonary rales disappearance time and adverse reactions were recorded. Results Total effective rate of treatment group was significantly higher than that of control group (P < 0.01). There was no significant difference in cough symptom scores between two groups before treatment and the seventh day of treatment (P > 0.05). The third day of treatment, the cough symptom score of treatment group was significantly lower than that of control group (P < 0.01). The time of fever regression in treatment group was shorter than that in control group (P < 0.05). There was no significant difference in the disappearance time of pulmonary rales between two groups (P > 0.05). There was no significant difference in the incidence of adverse reaction between two groups (P > 0.05). Conclusion Xingbei Zhike Granules combined with Western medicine in the adjuvant treatment of children with acute bronchitis, early medication can reduce cough symptoms in the third day of treatment, and can shorten the time of fever regression and improve the total effective rate, with low incidence of adverse reactions, which is worthy of clinical promotion.
2020, Vol. 17 
京公网安备 11010502046598号