Relationship between left atrial volume index and adverse cardiac events in patients with acute coronary syndrome and its diagnostic value
YI Zhengwei1 ZUO Hong1 WANG Yanchen2▲
1.Department of Cardiology, Xianyang Central Hospital, Shaanxi Province, Xianyang 712000, China;
2.Department of Geriatrics, Xianyang Central Hospital, Shaanxi Province, Xianyang 712000, China
Abstract：Objective To explore the relationship between left atrial volume index (LAVI) and major adverse cardiac events (MACE) in patients with acute coronary syndrome (ACS). Methods A total of 198 ACS patients who were followed up in Xianyang Central Hospital in Shaanxi Province from July 2018 to January 2019 were selected as the research objects. The follow-up time was six months. According to whether MACE occurred, they were divided into good prognosis group (115 cases) and poor prognosis group (83 cases). The differences in general information, LAVI, left atrial inner diameter (LAD), left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD) and left ventricular ejection fraction (LVEF) between the two groups were compared. The influencing factors of MACE were analyzed and the diagnostic efficacy of LAVI for MACE in ACS patients were tested. Results During the 6-month follow-up, the incidence of MACE in ACS patients was 41.92% (83/198). The age and Killp grade in the poor prognosis group were significantly higher than those in the good prognosis group, and the differences were statistically significant (P < 0.05). The LAVI, LAD, LVEDD and LVESD levels in the poor prognosis group were significantly higher than those in the good prognosis group, while the LVEF levels were significantly lower than those in the good prognosis group, and the differences were statistically significant (P ＜ 0.05). Logistic regression analysis showed that age, Killp grade, and LAVI were risk factors for MACE in ACS patients (OR ＞ 1, P ＜ 0.05), while LVEF was a protective factor (OR ＜ 1, P ＜ 0.05). The area under the ROC curve of LAVI predicting MACE in ACS patients was 0.874 (95%CI: 0.819-0.929, P ＜ 0.001), the cut-off value was 27.00, the accuracy was 0.671, the sensitivity and specificity were 81.90%, 85.20%, respectively. Conclusion LAVI is an independent risk factor for MACE in ACS patients, and it has a high diagnostic efficiency for MACE. According to this, early intervention can improve the prognosis of patients.
伊争伟1 左红1 王彦琛2▲. 左心房容积指数与急性冠脉综合征患者心脏不良事件的关系及其诊断价值[J]. 中国医药导报, 2021, 18(2): 52-55,60.
YI Zhengwei1 ZUO Hong1 WANG Yanchen2▲. Relationship between left atrial volume index and adverse cardiac events in patients with acute coronary syndrome and its diagnostic value. 中国医药导报, 2021, 18(2): 52-55,60.
2021, Vol. 18 
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