Research progress of inositol and insulin resistance in patients with polycystic ovary syndrome
LI Yangyang1 HOU Lihui2▲ LI Yan2 SUN Miao2 HAO Songli2 XIA Xiaoyan3
1.Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Department of Gynaecology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China; 3.Department of Traditional Chinese Medicine, Hainan Women and Children’s Medical Center, Hainan Province, Haikou 570206, China
Abstract：Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrine disorders in women. Typical clinical manifestations include oligo-ovulation and/or anovulation, excess androgens, and polycystic ovaries. PCOS is associated with an increased risk of diabetes mellitus type 2 and cardiovascular disease, and its main pathological mechanism is insulin resistance (IR). IR is a pathological association between PCOS metabolism and reproductive abnormalities. In the past decade, inositol has been increasingly used in the treatment of PCOS due to its natural, non-toxic, and effective properties. Compared with Metformin, insulin sensitizers containing inositol are recommended for the treatment of patients with PCOS. This review intends to discuss it from the point of view of inositol in the treatment of PCOS-IR.
李洋洋1 侯丽辉2▲ 李妍2 孙淼2 郝松莉2 夏小焱3. 肌醇与多囊卵巢综合征患者胰岛素抵抗的研究进展[J]. 中国医药导报, 2021, 18(12): 37-40.
LI Yangyang1 HOU Lihui2▲ LI Yan2 SUN Miao2 HAO Songli2 XIA Xiaoyan3. Research progress of inositol and insulin resistance in patients with polycystic ovary syndrome. 中国医药导报, 2021, 18(12): 37-40.
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