Analysis on the application situations of antibacterial agents in patients with community-acquired pneumonia
SHENG Chunqin1 ZHU Jingjie1 FENG Tingting2
1.Department of Pharmacy, Zhujiajiao People′s Hospital of Qingpu District, Shanghai 201700, China;
2.Department of Clinical Pharmacy, the First People′s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 201620, China
Abstract：Objective To explore the application situations of antibacterial agents in patients with community-acquired pneumonia (CAP) in Zhujiajiao People′s Hospital of Qingpu District in Shanghai City (“our hospital” for short), so as to improve the rationality of clinical application of antibacterial agents. Methods The medical history of patients diagnosed as CAP in all medical records of our hospital from January 2016 to June 2017 was summarized retrospectively. The type of antibacterial agents, frequency, drug combination, course of treatment, therapeutic effect and so on were analyzed statistically, the drug utilization index (DUI) was used as judging indicator of drug use. Results Among the antibacterial agents of CAP treatment in our hospital, the top three of use frequency was cephalosporins, fluoroquinolones and penicillins, the most widely-used was Cefotiam, all was in double combinations, the most common was combination of cephalosporins and fluoroquinolones [14 cases (33.33%)], the course was (5.28±3.83) d. Among 153 cases of patients, 50 cases (32.68%) were cured, 98 cases (64.05%) were improved, 2 cases (1.31%) were not healed, 3 cases (1.96%) were discharged or transferred. There were 4 kinds (26.67%) of antibacterial agents with DUI ranged from 0.9 to 1.1, 3 kinds (20.00%) of antibacterial agents with DUI＜0.9, 8 kinds (53.33%) of antibacterial agents with DUI＞1.1. Conclusion The total application situations of antibacterial agents in patients with CAP in our hospital are basically reasonable, but there are still some disadvantages and the drug use still needs further standardized.
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2018, Vol. 15 
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