Abstract：Objective To investigate the predictive value of serum soluble triggering receptor expresses on myeloid cells-1 (sTREM-1), monocytogenic protein 1 (MCP-1), and hypersensitivity C reactive protein (hs-CRP) levels after percutaneous coronary intervention (PCI) in elderly patients with acute myocardial infarction. Methods A total of 98 elderly patients with acute myocardial infarction admitted to Wuxi Second People’s Hospital of Jiangsu Province from March 2018 to March 2021 were selected. All subjects were followed up for six months. According to the incidence of restenosis, thy were divided into restenosis group and non-restenosis group. The risk factors of restenosis after PCI were analyzed; the receiver operating characteristic (ROC) curve was used to predict the diagnostic efficacy of different indicators for restenosis after PCI in elderly patients with acute myocardial infarction. Results Restenosis occurred in 11 of 98 patients, with an incidence of 11.22%. The levels of sTREM-1, MCP-1, and hs-CRP in restenosis group were higher than those in non-restenosis group (P < 0.05). sTREM-1, MCP-1, and hs-CRP were risk factors for restenosis after PCI in elderly patients with acute myocardial infarction (OR = 3.770, 5.376, 6.241, P < 0.05). The area under the curve of sTREM-1, MCP-1, and hs-CRP combined in predicting restenosis after PCI in elderly patients with acute myocardial infarction was higher than that predicted by each index alone (P < 0.05). Conclusion Serum sTREM-1, MCP-1, and hs-CRP are all associated with restenosis after PCI in elderly patients with acute myocardial infarction, and the predictive efficacy of the combination test is better.
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