Abstract：Gremlin 1 is a member of the transforming growth factor-β superfamily. Early studies have found that it participates in the formation, development, and differentiation of embryos and inhibits the formation of bone and cartilage. In glucose metabolism, Gremlin 1 can antagonize insulin action; in lipid metabolism, Gremlin 1 can regulate the formation and differentiation of human adipocytes and inhibit browning of white adipocytes. This article reviews the research progress of Gremlin 1 in glucolipid metabolism and related diseases in recent years, in order to provide theoretical basis for the treatment of glucolipid metabolism related diseases.
顾恬 赵丽 邓霞 杨玲 袁国跃▲. Gremlin 1在糖脂代谢及其相关疾病中的研究进展[J]. 中国医药导报, 2022, 19(27): 43-46.
GU Tian ZHAO Li DENG Xia YANG Ling YUAN Guoyue▲. Research progress of Gremlin 1 in glucolipid metabolic and related diseases. 中国医药导报, 2022, 19(27): 43-46.
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