Effect of psychological distress on sleep quality in patients with multiple myeloma during chemotherapy
JIA Lei1 WEN Xiaoyu2
1.Department of Hematology, West China School of Nursing, Sichuan University West China Hospital of Sichuan University, Sichuan Province, Chengdu 610000, China;
2.School of Nursing, Chengdu Medical University, Sichuan Province, Chengdu 610500, China
Abstract：Objective To analyze the effect of psychological distress on sleep quality in patients with multiple myeloma (MM) during chemotherapy. Methods A total of 100 MM patients who received chemotherapy in West China Hospital of Sichuan University from July 2020 to December 2021 were retrospectively collected and analyzed. All patients were evaluated by the degree of psychological distress (Kessler psychological distress scale [K10]) and sleep quality (Pittsburgh sleep quality index scale [PSQI]) after three courses of chemotherapy. The sleep quality of patients with different data characteristics and psychological distress was compared, and the relationship between psychological distress and sleep quality was analyzed by Spearman bivariate correlation. The effect of psychological disturbance on sleep quality was analyzed by linear regression. Results After three courses of chemotherapy, the average PSQI score of 100 patients was (9.02±2.37) points. The average K10 score was (25.60±6.76) points, among which 14, 29, 38, and 19 cases had low, lower, high, and higher degree of psychological distress, respectively. The total PSQI scores of patients with different age, disease ISS stage, education level and psychological distress were statistically significant (P＜0.05). Spearman bivariate correlation analysis showed that the degree of psychological distress of MM patients during chemotherapy was positively correlated with the total score of PSQI (rs=0.515, P＜0.05). Multiple linear regression analysis showed that age and degree of psychological distress were related to sleep quality of MM patients during chemotherapy (B=1.089, 1.353, P＜0.05). Conclusion The more serious the psychological distress of MM patients during chemotherapy, the worse their sleep quality. In order to improve their sleep quality and life quality, targeted measures should be taken to alleviate the psychological distress of MM patients and improve their sleep quality.
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