Clinical effect of self-made Ziyin Shugan Mingmu Prescription on patients with xerophthalmia with syndrome of yin deficiency of liver and kidney
YANG Lei1 WU Xiaoyang1 LUO Jihong1 XUE Linping2 LI Dujun1
1.Department of Ophthalmology, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Province, Wuhan 430074, China; 2.the First Clinical College, Hubei University of Traditional Chinese Medicine, Hubei Province, Wuhan 430061, China
Abstract：Objective To observe the clinical effect of self-made Ziyin Shugan Mingmu Prescription on patients with xerophthalmia with syndrome of yin deficiency of liver and kidney. Methods A total of 65 patients with xerophthalmia with syndrome of yin deficiency of liver and kidney treated in the Department of Ophthalmology, Hubei Provincial Hospital of Traditional Chinese Medicine from May 2019 to April 2021 were divided into control group (32 cases) and combination group (33 cases) according to random number table method. The control group was treated with Sodium Hyaluronate Eye Drops combined with acupuncture, and the combined group was treated with self-made Ziyin Shugan Mingmu Prescription on the basis of the treatment of control group. Ten days was taken as a course of treatment, and after two courses of treatment, the clinical efficacy of the two groups was compared. The changes of traditional Chinese medicine symptom score, breakup time of tear film (BUT), tear secretion, and corneal fluorescein staining (FL) scores before and after treatment were compared between the two groups. Results The clinical effect of the combined group was better than that of the control group, and the difference was statistically significant (P＜0.05). After treatment, the traditional Chinese medicine symptom scores and FL scores of the two groups were lower than those before treatment, and those of combined group were lower than those of control group, the differences were statistically significant (P＜0.05). After treatment, the BUT in both groups were longer than those before treatment, and the tear secretion were higher than those before treatment, and the BUT in the combined group was longer than that in the control group, and the tear secretion was higher than that in the control group, the differences were statistically significant (P＜0.05). Conclusion On the basis of Sodium Hyaluronate Eye Drops combined with acupuncture, the self-made Ziyin Shugan Mingmu Prescription has therapeutic effect on the clinical symptoms and indicators of patients with xerophthalmia with syndrome of yin deficiency of liver and kidney, highlighting the advantages of acupuncture and medicine in the treatment of eye diseases, worthy of further promotion and application.
杨磊1 吴晓阳1 罗继红1 薛林平2 李杜军1. 自拟滋阴疏肝明目方治疗肝肾阴虚型干眼症患者的临床效果[J]. 中国医药导报, 2023, 20(33): 117-121.
YANG Lei1 WU Xiaoyang1 LUO Jihong1 XUE Linping2 LI Dujun1. Clinical effect of self-made Ziyin Shugan Mingmu Prescription on patients with xerophthalmia with syndrome of yin deficiency of liver and kidney. 中国医药导报, 2023, 20(33): 117-121.
2023, Vol. 20 
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