Analysis on 249 cases of adverse drug reactions reports in Nanchong Central Hospital in 2018
TANG Zhiyong1,2 SU Qiang1,2 YANG Siyun1,2
1.Department of Clinical Medicine, Department of Pharmacy, Nanchong Central Hospital the Second Clinical Medical School of North Sichuan Medical College, Sichuan Province, Nanchong 637000, China;
2.Nanchong Key Laboratory of Individualized Drug Therapy, Department of Pharmacy, Nanchong Central Hospital the Second Clinical Medical School of North Sichuan Medical College, Sichuan Province, Nanchong 637000, China
Abstract：Objective To analyze the regularity and characteristics of adverse drug reactions (ADR) of Nanchong Central Hospital (“our hospital” for short) in 2018 to explore the possible causes and influencing factors of ADR, in order to promote clinical rational drug use and make sure the safe in patient. Methods A retrospective statistical analysis was performed on 249 ADR reports submitted by our hospital from January to December 2018, which were collected from the national ADR monitoring system network. Results In 249 ADR reports, the proportion of males (52.61%) was slightly higher than that of females (47.39%). The number of ADR patients over 60-80 years old was the most, accounting for 44.57%. The most common reaction type was “general ADR”, accounting for 50.21%. ADR caused by anti-tumor drugs was the first, accounting for 35.79%, followed by the ADR caused by anti infective drugs, accounting for 30.53%. Injection induced ADR accounted for 67.22% of the total. Circulatory system damage was the most common clinical manifestation in ADR, accounting for 36.65%. 99.60% of the patients were improved and recovered after ADR. Conclusion Clinical attention should be paid to the monitor of ADR, strengthening drug administration and establish a perfect medication supervision system. In clinical medication, we should strengthen the monitoring of the elderly patients, and try to reduce the use of injection drugs, so that we can take orally without intravenous medication. In the process of intravenous administration, we should pay close attention to the clinical symptoms of patients to ensure the safety of patients.
唐志勇1,2 苏强1,2 杨思芸1,2. 南充市中心医院2018年249例药品不良反应报告分析[J]. 中国医药导报, 2020, 17(19): 147-150.
TANG Zhiyong1,2 SU Qiang1,2 YANG Siyun1,2. Analysis on 249 cases of adverse drug reactions reports in Nanchong Central Hospital in 2018. 中国医药导报, 2020, 17(19): 147-150.
2020, Vol. 17 
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