Study on preparation technology and quality control of Jiawei Wuzi Yanzong Concentration Pills
OU YANG Ruoshui1，2 ZHONG Lanying1 WEN Guiqing1 ZHONG Nijun1 ZHUO Jinsheng3 XING Yitao4 WANG Lisheng1
1.College of Traditional Chinese Medicine, Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510403, China;
2.Southern College of Pharmacy，Guangdong Jiangmen Chinese Medical College, Guangdong Province, Jiangmen 529000, China;
3.Department of Pulmonary Diseases, Hainan Provincial Hospital of Traditional Chinese Medicine, Hainan Province, Haikou 570203, China;
4.Department of Urinary Surgery, Hainan Provincial Hospital of Traditional Chinese Medicine, Hainan Province, Haikou 570203, China
Abstract：Objective To establish a preparation method for Jiawei Wuzi Yanzong Concentration Pills and to test the quality of the concentration pills. Methods The concentration pills were prepared by plastic molded method. The formulation molding process was determined based on the soft material properties, moldability, moisture content and dissolution time limit, and the quality standard was tested according to the relevant requirements of Pharmacopoeia of the People’s Republic of China (2015 edition). Results The optimum forming process of Jiawei Wuzi Yanzong Concentration Pills was as follows: the relative density of thick paste was 1.40, the dosage ratio of medicine to honey was 1∶0.4, the powder fineness was 100 mesh, the drying temperature was 60℃ and the drying time was 10 h. The moisture content, dissolution time limit, weight difference and content of concentration pills were all in line with the regulations of Pharmacopoeia of the People’s Republic of China. Conclusion The molding process of concentration pills by this process is stable, reliable, simple and easy to operate, which provides a basis for industrial production.
2021, Vol. 18 
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