Effect of electric nape acupuncture combined with drugs on cognitive dysfunction of cerebral small vessel disease
LIU Huihui1 JIANG Wei2▲ SUN Zhongren1 CAO Yi1 JIAO Chuanxu1 ZHU Jinyi1 ZHANG Wenze1 ZHONG Sitong1
1.School of Acupuncture and Massage, Heilongjiang University of Chinese Medicine Department of Acupuncture, Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Teaching and Research Section of Massage, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150036, China
Abstract：of Acupuncture and Massage, Heilongjiang University of Chinese Medicine Department of Acupuncture, Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China; 2.Teaching and Research Section of Massage, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150036, China
[Abstract] Objective To investigate the effect of electric nape acupuncture combined with drugs on the cognitive dys function of patients with cerebral small vessel disease (CSVD). Methods A total of 72 patients with CSVD admitted to the outpatient department and ward of Second Affiliated Hospital of Heilongjiang University of Chinese Medicine from April 2018 to October 2020 were selected and they were divided into control group and treatment group by random number table method, with 36 patients in each group. The control group received oral medicine, acupuncture, symptomatic basic treatment. The treatment group was combined with electric nape acupuncture therapy on the basis of the control group, and both groups were treated for eight weeks. The Montreal cognitive assessment scale (MOCA) and the mini-mental state examination (MMSE) were used to assess the two groups before, two weeks and eight weeks after treatment, respectively. Results Of the 72 patients, 69 cases were actually observed and three cases were abscission. Among them, 35 cases in the control group and 34 cases in the treatment group completed observation. There were statistically significant differences in comparison between groups, time point comparison and interaction (P ＜ 0.05). Comparison within groups: MoCA and MMSE scores of the two groups after eight weeks of treatment were significantly higher than those before and after two weeks of treatment, the differences were statistically significant (all P ＜ 0.05). There were no significant differences in MoCA and MMSE scores between the two groups before treatment and two weeks after treatment (P ＞ 0.05). Comparison between groups: there were no significant differences in MoCA and MMSE scores between the two groups before treatment and two weeks after treatment (P ＞ 0.05). After eight weeks of treatment, MoCA and MMSE scores in the treatment group were significantly higher than those in the control group, and the differences were statistically significant (all P ＜ 0.05). Conclusion Electric nape acupuncture therapy can improve the MMSE and MoCA scores of patients with cognitive dysfunction of CSVD, and improve the cognitive function, and the longer the course of treatment, the better the benefit.
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