Clinical effect of Kelintong Capsules combined with Tamsulosin Hydrochloride Sustained-release Capsules in the treatment of lower ureteral calculi
YU Wenxiao1 PEI Xiaohua2 SUN Ning1 YANG Lijie1 YANG Yang1 YUAN Fang3
1.Beijing First Hospital of Integrated Traditional Chinese and Western Medicine, Beijing 100026, China;
2.Xiamen Hospital, Beijing University of Chinese Medicine, Fujian Province, Xiamen 361001, China;
3.Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China
Abstract：Objective To observe the clinical effect of Kelintong Capsules combined with Tamsulosin Hydrochloride Sustained-release Capsules in the treatment of lower ureteral calculi. Methods A total of 72 patients with lower ureteral calculi treated in Beijing First Hospital of Integrated Traditional Chinese and Western Medicine from July 2018 to June 2020 were selected as the research objects. The random number table method was used for grouping, and they were divided into treatment group and control group at a ratio of 1∶1, with 36 cases in each. The treatment group was treated with Kelintong Capsules combined with Tamsulosin Hydrochloride Sustained-release Capsules, and the control group was treated with Kelintong Capsules mimic combined with Tamsulosins Hydrochloride Sustained-release Capsules. The effects of Kelintong Capsules combined with Tamsulosin Hydrochloride Sustained-release Capsules in promoting stone removal, the number of days required for stone removal, reducing secondary lithotripsy, reducing renal colic, reducing the use of antibiotics and analgesics, and improving the clinical symptoms of traditional Chinese medicine were observed. Results During the treatment, four cases fell out, two cases in each group. The clinical treatment efficiency of the treatment group was higher than that of the control group, and the difference was statistically significant (P < 0.05). The need for a second lithotripsy in the treatment group was lower than that in the control group, and the difference was statistically significant (P < 0.05). The number of days required for stone removal and antibiotic use for the treatment group was shorter than that in the control group, and the difference was statistically significant (P < 0.05). There was no significant difference in the onset of renal colic between the two groups (P > 0.05). There was a statistically significant difference in the use of analgesics between the two groups (P < 0.05). After treatment, the scores of waist, abdomen and perineum pain, urination, hematuria, renal percussive pain and ureteral tenderness were lower in the two groups than before treatment, and the treatment group was lower than the control group, and the differences were statistically significant (P < 0.05). Conclusion After extracorporeal shock wave lithotripsy for patients with lower ureteral calculi, the use of Kelintong Capsules combined with Tamsulosin Hydrochloride Sustained-release Capsules for adjuvant treatment can significantly improve the clinical treatment effect of the patients, promote stone removal, quickly improve clinical symptoms, and reduce the incidence of postoperative complications.
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