Comparison of the effects of two different surgical methods in the treatment of papillary carcinoma of thyroid
YU Ming1 NA Zhaoyang1 YAN Changhong1 YU Xin2 YAN Jiangtao1 WU Xi1 LI Changbai1 BIAN Hui3
1.Department of Surgery, Qinhuangdao Orthopedic Hospital, Hebei Province, Qinhuangdao 066000, China;
2.Department of Aesthetic Medicine, Motherly and Child Care Center of Qinhuangdao, Hebei Province, Qinhuangdao 066000, China;
3.School of Mechanical Engineering, Yanshan University, Hebei Province, Qinhuangdao 066000, China
Abstract：Objective To compare and analyze the effect of two different surgical methods in the treatment of papillary carcinoma of thyroid. Methods A total of 84 patients with papillary thyroid carcinoma who underwent surgical treatment in Qinhuangdao Orthopedic Hospital, Hebei Province from January 2012 to December 2018 were selected as the research subjects. According to the random number table method, they were divided into control group and experimental group, with 42 cases in each group. The control group was treated with traditional multi-functional lateral neck preserving lymphadenectomy, and the experimental group was treated with multi-functional lateral neck preserving lymphadenectomy assisted by endoscopy. The surgical indexes (surgical time, blood loss, length of hospital stay), body stress-related serum indexes (C reactive protein, superoxide dismutase, malondialdehyde), incidence of complications, Vancouver scar scale (VSS), self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores were compared between the two groups. Results The surgical time of the experimental group was longer than that of the control group, the amount of blood loss, the total incidence of complications, VSS, SAS and SDS scores were lower than those of the control group, and the length of hospital stay of the experimental group was shorter than that of the control group, the differences were statistically significant (P ＜ 0.05). The levels of C reactive protein and malondialdehyde after surgery were higher than those before surgery, and the level of superoxide dismutase was lower than those before surgery, while the levels of C reactive protein and malondialdehyde in the experimental group were lower than those in the control group, and the level of superoxide dismutase in the experimental group was higher than those in the control group, with statistical significance (all P ＜ 0.05). Conclusion The effect of multi-functional lateral neck preserving lymph adenectomy assisted by endoscopy in the treatment of papillary carcinoma of thyroid is ideal, with the advantages of less blood loss, short hospital stay, low incidence of complications, beautiful incision, and can reduce the body stress reaction, anxiety and depression of patients, which is worthy of clinical application.
于铭1 那朝阳1 闫长红1 于锌2 闫江涛1 吴曦1 李长柏1 边辉3. 两种不同术式应用于甲状腺乳头状癌外科手术的效果比较[J]. 中国医药导报, 2021, 18(21): 71-74.
YU Ming1 NA Zhaoyang1 YAN Changhong1 YU Xin2 YAN Jiangtao1 WU Xi1 LI Changbai1 BIAN Hui3. Comparison of the effects of two different surgical methods in the treatment of papillary carcinoma of thyroid. 中国医药导报, 2021, 18(21): 71-74.
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