Tuberculosis induced by Sintilimab in patients with non-small cell lung cancer: a case report
LIU Di1,2 GONG Jun2 LIAO Zhengkai2 ZHOU Yunfeng2
1.Medicine Division, Wuhan University, Hubei Province, Wuhan 430072, China;
2.Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Hubei Province, Wuhan 430071, China
Abstract：Programmed death receptor-1/ programmed death-ligand-1 antibody has been widely used in the treatment of malignancies, it has been gradually reported as an immune-related adverse event. The case was a 67-year-old male patient with stage Ⅳ non-small cell lung cancer who was treated with second-line chemotherapy combined with Sintilimab after first-line treatment progression. Subsequently, the patient developed cough, wheezing and night sweats, further examination showed that mycobacterium tuberculosis was cultured, and he was diagnosed with tuberculous pleurisy. Tuberculosis induced by Sintilimab in patients with advanced non-small cell lung cancer after chemoradiotherapy has not been reported. In order to raise clinicians’ awareness of the potential risk of Sintilimab-induced tuberculosis, this paper is hereby reported.
刘娣1,2 龚俊2 廖正凯2 周云峰2. 信迪利单抗治疗非小细胞肺癌致结核病1例报道[J]. 中国医药导报, 2021, 18(23): 189-192.
LIU Di1,2 GONG Jun2 LIAO Zhengkai2 ZHOU Yunfeng2. Tuberculosis induced by Sintilimab in patients with non-small cell lung cancer: a case report. 中国医药导报, 2021, 18(23): 189-192.
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