Abstract：Objective To investigate the application of thromboela-stogram to guide blood transfusion in patients with traumatic massive hemorrhage and severe coagulation disorder. Methods A total of 107 patients with traumatic massive hemorrhage with severe coagulation disorder were selected from Lianyungang Second People’s Hospital of Lianyungang City, Jiangsu Province from December 2018 to December 2021, and were divided into routine group (54 cases with routine coagulation function detection) and study group (53 cases with thromboela-stogram detection) by random number table method. Activated partial thrombin time (APTT), prothrombin time (PT), thrombin time (TT), and fibrinogen (FIB) were measured before and after blood transfusion. The amounts of platelets, plasma, red suspension, and cryoprecipitate were counted during blood transfusion. The duration of hospitalization and ICU treatment and the incidence of complications during hospitalization were analyzed. Results After transfusion, APTT, PT, and TT in two groups were shorter than those before transfusion, while those in the study group were lower than those in the routine group; FIB was higher than that before transfusion, while that in the study group was higher than that in the routine group, and the differences were statistically significant (P＜0.05). The dosage of platelet, plasma, red suspension, and cryoprecipitate in the study group were lower those that in the routine group, and the differences were statistically significant (P＜0.05). There was no significant difference in hospital stay between the two groups (P＞0.05). The duration of ICU stay in the study group was shorter than that in the routine group, and the difference was statistically significant (P＜0.05). There was no significant difference in the total incidence of complications between the two groups (P＞0.05). Conclusion Thromboelastogram examination has a certain guiding value in guiding blood transfusion in patients with traumatic hemorrhage and severe coagulation disorder.
李茜1 吴新明1 樊继泷2 张林海1 霍霓1▲. 血栓弹力图在创伤大出血伴严重凝血功能障碍患者输血指导中的应用效果[J]. 中国医药导报, 2023, 20(31): 106-109.
LI Qian1 WU Xinming1 FAN Jilong2 ZHANG Linhai1 HUO Ni1▲. Application effect of thromboela-stogram in blood transfusion guidance for patients with traumatic massive hemorrhage and severe coagulation disorder. 中国医药导报, 2023, 20(31): 106-109.
2023, Vol. 20 
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