Study on chemical constituents from stems and leaves of Sedum aizoon L.
HAN Wei1 LI Mingxiao2 LYU Chongning2 HAO Yimeng2 LU Jincai2
1.Center for Drug Evaluation, China Food and Drug Administration, Beijing 100038, China;
2.Teaching and Research Office of Science of Chinese Medicinal Material Resources, College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Liaoning Province, Shenyang 110016, China
Abstract：Objective To study the chemical constituents in the stems and leaves of Sedum aizoon L. Methods The stems and leaves of Sedum aizoon L. was extracted with 70% ethyl alcohol to give ethanol extracts, which was further diluted by H2O and extracted with petroleum ether, chloroform, EtOAc and n-BuOH, respectively. They were isolated and purified by silica gel column chromatography, Sephadex LH-20 gel column chromatography and high performance liquid chromatography methods. The structures were elucidated based on the physic-chemical characters and spectral analysis. Results Nine compounds were obtained from n-BuOH extracts of 70% ethyl alcohol extracts from stems and leaves of Sedum aizoon L., which was kaempferol-3-O-β-D-glucopyranoside (1), myricetin-3-O-α-L-arabinopyranoside (2), quercetin-3-O-α-L-arabinopyranoside (3), herbacetin-3-O-α-L-arabinopyranoside (4), woodorien (5), vanilloloside (6), benzy-1-O-β-D-glucopyranoside (7), benzylethyl-O-β-D-glucopyranoside (8), benzylethyl-O-β-D-xylopyranosyl-(1→2)-O-β-D-glucopyranoside (9), respectively. Conclusion Compound 4 is a new compound, which has not yet been reported. Compounds 6-9 are isolated from genus Sedum for the first time.
韩炜1 李明晓2 吕重宁2 郝依萌2 路金才2. 景天三七茎叶的化学成分研究[J]. 中国医药导报, 2017, 14(27): 33-36.
HAN Wei1 LI Mingxiao2 LYU Chongning2 HAO Yimeng2 LU Jincai2. Study on chemical constituents from stems and leaves of Sedum aizoon L.. 中国医药导报, 2017, 14(27): 33-36.
2017, Vol. 14 
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