Abstract：Objective To investigate the effect of partial splenic artery embolization (PASE) in the treatment of simple grade Ⅲ and Ⅳ traumatic splenic rupture with hemorrhagic shock and its influence on immune function. Methods The clinical data of 86 patients with simple grade Ⅲ and Ⅳ traumatic splenic rupture complicated with hemorrhagic shock admitted to Bozhou People’s Hospital of Anhui Province from June 2017 to December 2020 were retrospectively analyzed, according to the operation method, they were divided into observation group and control group, with 43 cases in each group. The control group was treated with traditional surgery, and the observation group was treated with PASE. The perioperative situation, the changes of T lymphocyte subsets (CD3+, CD4+, CD4+/CD8+), and the incidence of complications were compared between the two groups. Results The operation time, systolic blood pressure recovery time, ambulation time, and hospitalization time in the observation group were shorter than those in the control group, and the intraoperative blood loss of the observation group was less than those in the control group, and the differences were statistically significant (P ＜ 0.05); the differences of CD3+, CD4+, CD4+/CD8+ between the two groups, time point and interaction compared were statistically significant (P ＜ 0.05); the total incidence of complications the obseruation group was lower than that of the control group (P ＜ 0.05). Conclusion PASE in treatment of simple grade Ⅲ and Ⅳ traumatic splenic rupture with hemorrhagic shock have obvious effect, which is worth promoting.
张玉新 闫金亮 田景中. PASE治疗单纯性Ⅲ、Ⅳ级创伤性脾破裂伴失血性休克的效果及对免疫功能的影响[J]. 中国医药导报, 2021, 18(31): 111-114.
ZHANG Yuxin YAN Jinliang TIAN Jingzhong. Effect of PASE in the treatment of simple grade Ⅲ and Ⅳ traumatic splenic rupture with hemorrhagic shock and its influence on immune function #br#. 中国医药导报, 2021, 18(31): 111-114.
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