中国医药导报
中国医药期刊欢迎您 今天是   2025年4月5日星期六
设为首页 | 加入收藏 
 
        首 页      期刊介绍      下载中心      关于本刊      投稿指南      期刊订阅      在线留言      广告合作      联系我们      返回中国当代医药网
中国医药导报
  临床医学-泌尿系统疾病 本期目录 | 过刊浏览 | 高级检索 |
坦索罗辛与左氧氟沙星对慢性前列腺炎的临床效果
李月兵      邢家龙      宗朝晖      张华俊
江苏省如皋市人民医院泌尿外科,江苏如皋   226500
Clinical effect of Tansoloxin and Levofloxacin in the treatment of chronic prostatitis
LI Yuebing   XING Jialong   ZONG Zhaohui   ZHANG Huajun
Department of Urology, Rugao People’s Hospital, Jiangsu Province, Rugao   226500, China
全文: PDF (597 KB)   HTML (1 KB) 
输出: BibTeX | EndNote (RIS)      
摘要 目的 分析坦索罗辛与左氧氟沙星对慢性前列腺炎的临床效果。 方法 选取江苏省如皋市人民医院2017年4月—2020年5月收治的慢性前列腺炎患者86例,根据治疗方案分为对照组和观察组,各43例。对照组给予左氧氟沙星治疗,观察组给予坦索罗辛与左氧氟沙星联合治疗,分析两组治疗后的临床效果。 结果 治疗3周后,观察组总有效率高于对照组,差异有统计学意义(P < 0.05)。治疗前,两组前列腺液中白细胞介素(IL)-2、IL-6、巨噬细胞炎性蛋白-2(MIP-2)、巨噬细胞炎性蛋白-1α(MIP-1α)、白细胞、卵磷脂小体比较,差异无统计学意义(P > 0.05)。治疗3周后,两组前列腺液中卵磷脂小体较治疗前上升,IL-2、IL-6、MIP-2、MIP-1α及白细胞较治疗前下降,且观察组前列腺液中卵磷脂小体高于对照组,IL-2、IL-6、MIP-2、MIP-1α及白细胞低于对照组(P < 0.05)。治疗前,两组国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)评分比较,差异无统计学意义(P > 0.05)。治疗后,两组疼痛、排尿症状、生活质量及NIH-CPSI总分较治疗前下降,且观察组低于对照组(P < 0.05)。 结论 坦索罗辛与左氧氟沙星联合治疗慢性前列腺炎可减轻炎症,改善症状,提高疗效。
服务
把本文推荐给朋友
加入我的书架
加入引用管理器
E-mail Alert
RSS
作者相关文章
李月兵 邢家龙 宗朝晖 张华俊
关键词 坦索罗辛左氧氟沙星慢性前列腺炎症状    
Abstract:Objective To analyze the clinical effect of Tansoloxin and Levofloxacin in the treatment of chronic prostatitis. Methods From April 2017 to May 2020, 86 patients with chronic prostatitis were divided into control group and observation group according to the treatment plan, with 43 cases in each group. The control group was treated with Levofloxacin, the observation group was treated with Tansororosin and Levofloxacin. The clinical effect of two groups after treatment was analyzed. Results After three weeks of treatment, the total effective rate in the observation group was higher than that in the control group (P < 0.05). There were no significant differences in interleukin (IL)-2, IL-6, macrophage inflammatory protein-2 (MIP-2), macrophage inflammatory protein-1α (MIP-1), leukocyte and lecithin corpuscles between the two groups before treatment (P > 0.05). After three weeks of treatment the lecithin bodies in prostate fluid in the two groups increased, IL-2, IL-6, MIP-2, MIP-1α and white blood cells decreased compared with those before treatment, and the lecithin bodies in prostate fluid in the observation group were higher than those in the control group, and the inflammatory factors and white blood cells were lower than those in the control group (P < 0.05). There was no significant difference in national institutes of health chronic prostatitis index (NIH-CPSI) score between the two groups before treatment (P > 0.05). The pain, voiding symptoms, quality of life and total score of NIH-CPSI in the two groups decreased compared with before treatment, and those in the observation group were lower than the control group (P < 0.05). Conclusion Tansoloxin combined with Levofloxacin in the treatment of chronic prostatitis can reduce inflammation, improve symptoms and improve the curative effect.
Key wordsTansoloxin    Levofloxacin    Chronic prostatitis    Symptoms
    
基金资助:国家自然科学基金资助项目(81771571)。
作者简介: 李月兵(1982.4-),男,硕士;研究方向:结石,前列腺。
引用本文:   
李月兵 邢家龙 宗朝晖 张华俊 . 坦索罗辛与左氧氟沙星对慢性前列腺炎的临床效果[J]. 中国医药导报, 2021, 18(15): 84-87.
LI Yuebing XING Jialong ZONG Zhaohui ZHANG Huajun. Clinical effect of Tansoloxin and Levofloxacin in the treatment of chronic prostatitis. 中国医药导报, 2021, 18(15): 84-87.
链接本文:  
https://www.yiyaodaobao.com.cn/CN/     或     https://www.yiyaodaobao.com.cn/CN/Y2021/V18/I15/84

 

中华人民共和国互联网药品信息服务资格证书(京)-非经营性-2016-0092
京ICP11001767号-2  京公网安备 11010502046598号  期刊出版许可证 广告经营许可证
信息产业部备案管理系统网址 http://beian.miit.gov.cn/state/outPortal/loginPortal.action
投稿热线:010-59626203
本刊地址:北京市朝阳区东四环中路78号楼(大成国际中心B1座)8B02室 邮编:100124
传真:010-59626204 投稿信箱:ddyy@vip.163.com
版权所有:中文传媒集团北京期刊有限公司
技术支持:北京玛格泰克科技发展有限公司