Role of autophagy-related regulatory signaling pathways in bone remodeling and the progress of traditional Chinese medicine prevention and treatment
MO Yafeng1 HU Minli2 TANG Yanghua1 LI Guosong1 XIN Dawei1 XIONG Zhenfei1
1.Department of Orthopedics, Xiaoshan District Hospital of Traditional Chinese Medicine of Hangzhou City Jiangnan Hospital Affiliated to Zhejiang Chinese Medicine University, Zhejiang Province，Hangzhou 311201, China;
2.Beigan Branch, the General Hospital of Xiaoshan Hospital, Zhejiang Province, Hangzhou 311202, China
Abstract：Bone remodeling is a bioremediation process with many influencing factors. Bone nonunion prolongs the treatment period of the disease, which is a thorny problem in the treatment of fracture patients. At present, the factors affecting bone remodeling and the mechanism of the related drugs promoting bone remodeling have not been fully clarified. Autophagy plays an important role in the life activities of osteoblasts, osteoclasts and osteocytes, so the regulation of autophagy has important research value in bone remodeling. In this paper, the mechanism of action of autophagy related signal pathways in bone remodeling and traditional Chinese medicine prevention and treatment of bone nonunion are reviewed, to open up new ideas and methods for the treatment of bone nonunion.
莫亚峰1 胡敏利2 汤样华1 李国松1 辛大伟1 熊振飞1. 自噬相关调控信号通路在骨重塑中的作用及中医药防治进展[J]. 中国医药导报, 2021, 18(24): 40-43.
MO Yafeng1 HU Minli2 TANG Yanghua1 LI Guosong1 XIN Dawei1 XIONG Zhenfei1. Role of autophagy-related regulatory signaling pathways in bone remodeling and the progress of traditional Chinese medicine prevention and treatment. 中国医药导报, 2021, 18(24): 40-43.
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