Research progress on molecular mechanism related pathway of Sishen Pills in the treatment of ulcerative colitis
XIA Guozhen1 LIU Li1 LIANG Yanni2 LI Yi3 ZHANG Congwei3 LI Yao1
1.The First Clinical Medical College, Shaanxi University of Traditional Chinese Medicine, Shaanxi Province, Xianyang 712046, China;
2.Cooperative Innovation Center of Traditional Chinese Medicine Resources Industrialization, Shaanxi University of Traditional Chinese Medicine, Shaanxi Province, Xianyang 712000, China;
3.Department of Gastroenterology, Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Shaanxi Province, Xianyang 712000, China
Abstract：Ulcerative colitis (UC) is a chronic inflammatory disease affecting the colon. Western medicine treatment of UC has disadvantages such as high price and many side effects, etc. As a traditional Chinese medicine, Sishen Pills can effectively treat UC. In terms of molecular mechanism, NF-κB signaling pathway, JAK/STAT signaling pathway, PI3K/Akt signaling pathway, mitogen-activated protein kinase signaling pathway, Wnt/β-catenin signaling, Th17/Treg signaling pathways, Th1/Th2 signaling pathways. This article mainly investigates the related signaling pathways of Sishen Pills when treating the UC, hoping to provide some experimental basis.
夏国珍1 刘力1 梁艳妮2 李毅3 张聪伟3 李瑶1. 四神丸治疗溃疡性结肠炎分子机制研究进展[J]. 中国医药导报, 2020, 17(33): 46-48.
XIA Guozhen1 LIU Li1 LIANG Yanni2 LI Yi3 ZHANG Congwei3 LI Yao1. Research progress on molecular mechanism related pathway of Sishen Pills in the treatment of ulcerative colitis. 中国医药导报, 2020, 17(33): 46-48.
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2020, Vol. 17 
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